Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Z-Butylidenephthalide SCHEMBL30268972 | 1.00 | TRPA1 (1.00) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL27581583 | 1.00 | TRPA1 (1.00) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL29372485 | 1.00 | TRPA1 (1.00) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| (E)-Butylidenephthalide SCHEMBL783051 | 1.00 | TRPA1 (1.00) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL290482 | 1.00 | TRPA1 (1.00) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL28057404 | 1.00 | TRPA1 (1.00) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL27312198 | 0.98 | TRPA1 (0.96) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL28057401 | 0.92 | TRPA1 (0.84) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL6530791 | 0.89 | TRPA1 (0.81) | TRPA1ALDH1A1TSHRMAPK1KDM4E | |
| Z-Butylidenephthalide SCHEMBL28165145 | 0.89 | TRPA1 (0.79) | TRPA1ALDH1A1TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2135 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260068882-A1 | ARTHROPOD CONTROLLING COMPOSITION | FIRMENICH & CIE (CH) | 2026-03-12 | — | — | US | claimed |
| US-12568998-B2 | Flavouring composition with balanced taste profile | SYMRISE AG (DE) | 2026-03-10 | — | — | US | claimed |
| US-20250325463-A1 | COMPOSITIONS (III) | SYMRISE AG (DE) | 2025-10-23 | — | — | US | claimed |
| US-20250295123-A1 | Arthropod Control Compositions | FIRMENICH & CIE (CH) | 2025-09-25 | — | — | US | claimed |
| EP-4444108-B1 | ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT | SYMRISE AG (DE) | 2025-09-10 | — | — | EP | claimed |
| EP-3466281-B1 | TOBACCO SMOKE FILTER | FILTRONA PTE LTD (SG) | 2025-08-13 | — | — | EP | claimed |
| US-20250235498-A1 | METHODS OF TREATING OR PREVENTING RESPIRATORY DISEASE WITH HOUTTUYNIA CORDATA THUNB-BASED AEROSOL INHALATION THERAPY | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2025-07-24 | — | — | US | claimed |
| EP-4583708-A1 | ARTHROPOD CONTROL COMPOSITIONS | Firmenich SA (CH) | 2025-07-16 | — | — | EP | claimed |
| US-20250212873-A1 | VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-07-03 | — | — | US | claimed |
| EP-4570901-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | Buddhist Tzu Chi Medical Foundation (TW) | 2025-06-18 | — | — | EP | claimed |
| US-20040220378-A1 | Compositions for golf equipment | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-04 | — | — | US | claimed |
| CN-1511529-A | Medicine for treating cerebrovascular desease | 广州中医药大学科技产业园有限公司 | 2004-07-14 | — | — | CN | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| WO-2001001996-A9 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS | UNIV WESTERN AUSTRALIA (AU) | 2002-09-12 | — | — | WO | claimed |
| WO-2001001996-A1 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS | UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2001-01-11 | — | — | WO | claimed |
| CN-1041725-C | Method for synthetising 3-butenyl phthalide | UNIV LANZHOU (CN) | 1999-01-20 | — | — | CN | claimed |
| EP-0786944-B1 | POULTRY FEED ADDITIVE COMPOSITION | CRINA (CH) | 1998-08-12 | — | — | EP | claimed |
| EP-0786944-A1 | POULTRY FEED ADDITIVE COMPOSITION | CRINA S.A. (CH) | 1997-08-06 | — | — | EP | claimed |
| WO-1996013175-A1 | POULTRY FEED ADDITIVE COMPOSITION | CRINA S.A. (CH) | 1996-05-09 | — | — | WO | claimed |
| CN-1086814-A | A kind of method of synthetic 3-butylidene phthalide | UNIV LANZHOU (CN) | 1994-05-18 | — | — | CN | claimed |