SCHEMBL29048472

SCHEMBL29048472

CC1(C)CCC(c2ccc(F)cc2)=NC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.37
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MAOB P27338 2/20 0.35
ABL1 P00519 1/20 0.35
RIN1 Q13671 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPY5R Q15761 3/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
ALPL P05186 1/20 0.33
CYP17A1 P05093 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP11B2 P19099 2/20 0.33
HTT P42858 2/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
GCGR P47871 1/20 0.32
PLA2G7 Q13093 1/20 0.32
CYP11B1 P15538 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22040138 0.76 MAOB (0.37) MAPK14PTGS1PTGS2MAOBABL1
SCHEMBL23878282 0.68 POLB (0.41) MAOBCYP3A4HTT
SCHEMBL24414772 0.67 CHRNB4 (0.55) MAPK14CHRNB4CHRNA3NPC1RAB9A
SCHEMBL19072298 0.67 NPC1 (0.42) MAPK14PTGS1PTGS2MAOBHTT
SCHEMBL8151174 0.66 CHRNB4 (0.64) MAPK14CHRNB4CHRNA3NPC1RAB9A
SCHEMBL24363981 0.63 HTR2A (0.42) MAPK14
SCHEMBL23188911 0.60 MAPT (0.37) MAPK14PTGS1PTGS2MAOBHTT
SCHEMBL1907131 0.60 NPY5R (0.38) NPY5RCHRNB4CHRNA3
SCHEMBL23960356 0.60 LPL (0.35) PTGS1PTGS2NPY5RALPLHTT
SCHEMBL20622620 0.59 OPRD1 (0.43) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed