(R)-3-Hydroxybutanoate

(R)-3-Hydroxybutanoate

SCHEMBL29048487

COC(=O)C[C@@H](C)O.C[C@@H](O)CC(=O)O

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
MAPT P10636 2/20 0.35
KCNA5 P22460 1/20 0.35
GABRR1 P24046 2/20 0.34
LMNA P02545 1/20 0.34
RAB9A P51151 1/20 0.34
CACNA2D1 P54289 2/20 0.33
CACNB3 P54284 1/20 0.33
CACNA1C Q13936 1/20 0.33
PGR P06401 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CACNA2D2 Q9NY47 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55045 0.91
SCHEMBL53570 0.91
SCHEMBL2544991 0.91
SCHEMBL28902938 0.88
Methyl Alcohol SCHEMBL27770158 0.88 TSHR (0.46) TSHRHSD17B10MGAMGAASI
3-Hydroxybutyric Acid, (+/-)- SCHEMBL27749364 0.84 ALDH1A1 (0.48) TSHRSLC22A6SMN1; SMN2MAPTGABRR1
Trimethylammonium SCHEMBL27917620 0.84 TSHR (0.42) TSHRHSD17B10MGAMGAASI
3-Hydroxybutyric Acid, (+/-)- SCHEMBL27742464 0.83 GPR84 (0.44) TSHRSLC22A6HSD17B10MAPTGABRR1
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 0.83 SLC22A6 (0.56) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
(R)-3-Hydroxybutanoate SCHEMBL60959 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396163-A Method for one-step catalytic synthesis of (R) -3-hydroxybutyric acid oligomer by using solid acid catalyst 东莞理工学院 2023-07-07 CN disclosed