Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 15/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048688 | 0.89 | PIK3CG (0.40) | MAP4K4SHMT1CYP3A4CYP2D6PSEN1 | |
| SCHEMBL30526039 | 0.88 | RAPGEF4 (0.41) | RAPGEF4 | |
| SCHEMBL29048689 | 0.77 | MAP4K4 (0.40) | MAP4K4SHMT1PIK3CG | |
| SCHEMBL29048631 | 0.77 | ROS1 (0.37) | MAP4K4SHMT1PIK3CG | |
| SCHEMBL30525983 | 0.76 | AGPAT2 (0.45) | SHMT1PIK3CG | |
| SCHEMBL29048615 | 0.76 | RAPGEF4 (0.38) | RAPGEF4 | |
| SCHEMBL28352643 | 0.76 | RAPGEF4 (0.47) | RAPGEF4 | |
| SCHEMBL29048658 | 0.75 | MAPK10 (0.44) | RAPGEF4CYP2D6 | |
| SCHEMBL31368585 | 0.74 | AGPAT2 (0.46) | RAPGEF4 | |
| SCHEMBL21670520 | 0.74 | AGPAT2 (0.46) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446770-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same | 百乐墨水株式会社 | 2023-08-08 | — | — | CN | disclosed |