SCHEMBL21670520

SCHEMBL21670520

CCOc1cc(Cl)ccc1-c1cc(-c2ccc(Nc3c(C)cc(C)cc3C)cc2)cc(-c2ccc(Cl)cc2OCC)n1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AGPAT2 O15120 14/20 0.46
CCNT1 O60563 3/20 0.43
CDK9 P50750 3/20 0.43
RAPGEF4 Q8WZA2 2/20 0.39
TRPV1 Q8NER1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31368585 1.00 AGPAT2 (0.46) AGPAT2CCNT1CDK9RAPGEF4TRPV1
SCHEMBL21670509 0.89 AGPAT2 (0.54) AGPAT2CCNT1CDK9
SCHEMBL31368584 0.89 AGPAT2 (0.54) AGPAT2CCNT1CDK9
SCHEMBL21670567 0.88 KDM4E (0.41) AGPAT2RAPGEF4
SCHEMBL30525991 0.86 ENPP3 (0.46) AGPAT2RAPGEF4
SCHEMBL21670516 0.86 ENPP3 (0.46) AGPAT2RAPGEF4
SCHEMBL30526039 0.84 RAPGEF4 (0.41) AGPAT2RAPGEF4
SCHEMBL21670506 0.79 AGPAT2 (0.43) AGPAT2CCNT1CDK9TRPV1
SCHEMBL29048615 0.78 RAPGEF4 (0.38) CCNT1CDK9RAPGEF4
SCHEMBL21670537 0.77 LMNA (0.44) AGPAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed