Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048679 | 0.94 | SYK (0.43) | MAPTKDRPLK1LMNAKDM4E | |
| SCHEMBL29048609 | 0.91 | KDM4E (0.45) | MAPTLMNAKDM4ETP53SMN1; SMN2 | |
| SCHEMBL29048664 | 0.91 | AGPAT2 (0.39) | MAPTLMNAKDM4ETP53SMN1; SMN2 | |
| SCHEMBL29048634 | 0.90 | MAPKAPK2 (0.42) | MAPTKDRPLK1LMNAKDM4E | |
| SCHEMBL29048661 | 0.89 | MAPT (0.40) | MAPTKDRPLK1LMNAKDM4E | |
| SCHEMBL29048612 | 0.89 | CYP2D6 (0.45) | MAPTLMNAKDM4ETP53SMN1; SMN2 | |
| SCHEMBL30525974 | 0.88 | LMNA (0.47) | MAPTPDE4BPDE4DKDRPLK1 | |
| SCHEMBL21670570 | 0.88 | LMNA (0.47) | MAPTPDE4BPDE4DKDRPLK1 | |
| SCHEMBL29048622 | 0.88 | KDM4E (0.36) | MAPTKDRPLK1LMNAKDM4E | |
| SCHEMBL29048683 | 0.88 | FGFR2 (0.41) | MAPTKDRLMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446770-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same | 百乐墨水株式会社 | 2023-08-08 | — | — | CN | disclosed |