SCHEMBL21670570

SCHEMBL21670570

CCOc1ccc(-c2cc(-c3ccc(Nc4ccc(OC)cc4)cc3)cc(-c3ccc(OCC)cc3OCC)n2)c(OCC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
KDM4E B2RXH2 3/20 0.47
TP53 P04637 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PDE4B Q07343 1/20 0.46
PDE4D Q08499 1/20 0.46
MAPT P10636 8/20 0.45
KDR P35968 1/20 0.42
PLK1 P53350 1/20 0.42
HTT P42858 2/20 0.41
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525974 1.00 LMNA (0.47) LMNAKDM4ETP53SMN1; SMN2PDE4B
SCHEMBL21670518 0.94 KDM4E (0.46) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL30525957 0.94 KDM4E (0.46) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL21670540 0.91 KDM4E (0.52) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL30525979 0.91 KDM4E (0.52) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL21670537 0.91 LMNA (0.44) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL30525968 0.91 LMNA (0.44) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL30525958 0.89 KDM4E (0.43) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL21670523 0.89 KDM4E (0.43) LMNAKDM4ETP53SMN1; SMN2MAPT
SCHEMBL21670528 0.88 MAPT (0.44) LMNAKDM4ETP53SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed