Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397637 | 1.00 | MAPT (0.52) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL12774397 | 0.79 | MAPT (0.58) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL339812 | 0.77 | MAPT (0.71) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| Hydrochloric Acid SCHEMBL11729665 | 0.75 | MAPT (0.53) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL26013299 | 0.71 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL5538708 | 0.71 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| Formaldehyde SCHEMBL27831678 | 0.71 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8216313 | 0.71 | MAPT (0.69) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL6215213 | 0.70 | MAPT (0.67) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL11721119 | 0.69 | MAPT (0.54) | MAPTMAPK1TDP1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574054-A | Selective estrogen receptor down regulator compound, preparation method and application | 南京中医药大学 | 2023-08-11 | — | — | CN | disclosed |