SCHEMBL12774397

SCHEMBL12774397

CN(C)c1ccccc1OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.58
MAPK1 P28482 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
LIPE Q05469 1/20 0.53
HTR1A P08908 4/20 0.50
DRD2 P14416 1/20 0.50
LTA4H P09960 1/20 0.47
MAPK14 Q16539 1/20 0.47
CCR5 P51681 1/20 0.46
ADRA1D P25100 3/20 0.46
ADRA1A P35348 3/20 0.46
ADRA1B P35368 3/20 0.46
GAA P10253 1/20 0.46
BRD4 O60885 1/20 0.46
ALPG P10696 1/20 0.46
PTK2B Q14289 1/20 0.46
CYP19A1 P11511 1/20 0.46
CCNB2 O95067 1/20 0.45
CDK1 P06493 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11721119 0.84 MAPT (0.54) MAPTMAPK1TDP1L3MBTL1LIPE
Hydrochloric Acid SCHEMBL11729665 0.84 MAPT (0.53) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL12774122 0.82 MAPT (0.47) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL15871969 0.81 CYP19A1 (0.50) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL14228410 0.81 CCR5 (0.51) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL31397637 0.79 MAPT (0.52) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL29048752 0.79 MAPT (0.52) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL339812 0.79 MAPT (0.71) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL17653407 0.79 LMNA (0.49) MAPTMAPK1TDP1L3MBTL1LIPE
SCHEMBL2863207 0.78 ALDH1A1 (0.52) MAPTTDP1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MAPT 2719/4885MAPK1 1478/4885TDP1 4437/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MAPT 2719/4885MAPK1 1478/4885TDP1 4437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.