Ether

Ether

SCHEMBL29049196

CC(=O)O.CCC(O)O.CCOCC

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
TSHR P16473 3/20 0.41
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FFAR3 O14843 2/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.32
CYP2D6 P10635 1/20 0.31
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL115545 0.86
Ether SCHEMBL20338904 0.86 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10FFAR3
Ether SCHEMBL28328411 0.86 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10FFAR3
Ether SCHEMBL7115101 0.86 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10FFAR3
Acetic Acid SCHEMBL10353591 0.86 FFAR3 (0.50) ALDH1A1TSHRFFAR3LCKFYN
Acetic Acid SCHEMBL1362080 0.86
Ether SCHEMBL28393262 0.86 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10FFAR3
Ether SCHEMBL8375323 0.86 TSHR (0.42) ALDH1A1TSHRLMNAHSD17B10THRB
Ether SCHEMBL4796022 0.86 TSHR (0.42) ALDH1A1TSHRLMNAHSD17B10THRB
Ether SCHEMBL5798215 0.85 ALDH1A1 (0.48) ALDH1A1TSHRLMNAHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114660896-B Composition for forming silicon-containing resist underlayer film, pattern forming method, and silicon compound 信越化学工业株式会社 2024-06-11 CN disclosed
CN-118146606-A Bioelectrode composition, bioelectrode, and bioelectrode manufacturing method 信越化学工业株式会社 2024-06-07 CN disclosed
CN-118044816-A Bioelectrode, bioelectrode composition, and bioelectrode manufacturing method 信越化学工业株式会社 2024-05-17 CN disclosed
CN-114829457-B Polysiloxane copolymer, method of preparing the same, and resin composition including the same 胡网加成股份有限公司 2024-05-03 CN disclosed
CN-108375878-B Polymerizable composition, method for producing cured film, and cured film 东京应化工业株式会社 2023-12-08 CN disclosed
CN-116917378-A Photosensitive composition comprising organometallic compound and polysiloxane copolymer and method for preparing the same 胡网加成股份有限公司 2023-10-20 CN disclosed
CN-116804825-A Composition for forming silicon-containing metal hard mask and pattern forming method 信越化学工业株式会社 2023-09-26 CN disclosed
CN-111208710-B Iodine-containing thermosetting silicon-containing material, resist underlayer film forming composition for extreme ultraviolet lithography containing the same, and pattern forming method 信越化学工业株式会社 2023-08-22 CN disclosed
CN-111458980-B Composition for forming underlayer film of silicon-containing resist and method for forming pattern 信越化学工业株式会社 2023-08-11 CN disclosed
CN-116514161-A Nanoparticle, nanoparticle dispersion liquid, and method for producing nanoparticle 东京应化工业株式会社 2023-08-01 CN disclosed