⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208726 | 0.72 | GRM5 (0.36) | — | |
| SCHEMBL210402 | 0.69 | HRH3 (0.35) | — | |
| SCHEMBL29050286 | 0.64 | GRM5 (0.39) | — | |
| SCHEMBL18278576 | 0.63 | HTR6 (0.33) | — | |
| SCHEMBL23109923 | 0.62 | RAD52 (0.40) | — | |
| SCHEMBL14925519 | 0.62 | GRM5 (0.40) | — | |
| SCHEMBL23374985 | 0.61 | PDCD1 (0.34) | — | |
| SCHEMBL18375024 | 0.60 | GRM5 (0.38) | — | |
| Lithium Ion SCHEMBL27175184 | 0.59 | GRM5 (0.38) | — | |
| SCHEMBL24585187 | 0.59 | CYP3A4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568303-A | Dihydrofuranopyridine derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116568303-A | Dihydrofuranopyridine derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2023-08-08 | — | — | CN | disclosed |