Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138014 | 0.85 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL3138004 | 0.85 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL3140091 | 0.85 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL7489800 | 0.84 | ALDH1A1 (0.59) | ALDH1A1GBA1SIGMAR1KDM4EHRH3 | |
| SCHEMBL28865568 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SIGMAR1KDM4EHRH3MEN1 | |
| SCHEMBL104186 | 0.84 | SIGMAR1 (0.51) | MAPTSIGMAR1 | |
| SCHEMBL104699 | 0.84 | SIGMAR1 (0.51) | MAPTSIGMAR1 | |
| SCHEMBL104187 | 0.84 | SIGMAR1 (0.51) | MAPTSIGMAR1 | |
| SCHEMBL14528988 | 0.84 | KDM4E (0.45) | ALDH1A1SOS1SIGMAR1KDM4E | |
| SCHEMBL17927250 | 0.84 | KDM4E (0.45) | ALDH1A1SOS1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568301-A | Bicyclic compounds for treating diseases and uses thereof | 雅斯娜制药公司 | 2023-08-08 | — | — | CN | disclosed |