Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967247 | 0.85 | GAA (0.49) | HPGDMEN1KMT2AGAAHSD11B1 | |
| SCHEMBL29967082 | 0.85 | GAA (0.49) | HPGDMEN1KMT2AGAAHSD11B1 | |
| Hydrochloric Acid SCHEMBL3714221 | 0.83 | HPGD (0.48) | HPGDMEN1KMT2AGAAHSD11B1 | |
| SCHEMBL30671639 | 0.83 | GAA (0.50) | HPGDMEN1KMT2AGAACA1 | |
| Trifluoroacetic Acid SCHEMBL1763151 | 0.83 | SIGMAR1 (0.47) | HPGDGAASMODPP4CA1 | |
| Trifluoroacetic Acid SCHEMBL1763153 | 0.83 | SIGMAR1 (0.47) | HPGDGAASMODPP4CA1 | |
| SCHEMBL13727453 | 0.82 | HPGD (0.49) | HPGDGAAHSD11B1DPP4MGLL | |
| SCHEMBL20750497 | 0.82 | HPGD (0.49) | HPGDGAAHSD11B1DPP4MGLL | |
| SCHEMBL1090149 | 0.81 | SIGMAR1 (0.54) | HPGDTSHRGAASMODPP4 | |
| SCHEMBL1763575 | 0.81 | SIGMAR1 (0.54) | HPGDTSHRGAASMODPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568301-A | Bicyclic compounds for treating diseases and uses thereof | 雅斯娜制药公司 | 2023-08-08 | — | — | CN | disclosed |