Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967082 | 1.00 | GAA (0.49) | GAAHPGDGHSRDPP4CA1 | |
| Hydrochloric Acid SCHEMBL3714221 | 0.99 | HPGD (0.48) | GAAHPGDGHSRDPP4CA1 | |
| SCHEMBL30671639 | 0.87 | GAA (0.50) | GAAHPGDCA1CA2CA4 | |
| SCHEMBL20750497 | 0.85 | HPGD (0.49) | GAAHPGDDPP4CA1CA2 | |
| SCHEMBL13727453 | 0.85 | HPGD (0.49) | GAAHPGDDPP4CA1CA2 | |
| SCHEMBL1763575 | 0.85 | SIGMAR1 (0.54) | GAAHPGDDPP4CA1CA2 | |
| SCHEMBL1090152 | 0.85 | SIGMAR1 (0.54) | GAAHPGDDPP4CA1CA2 | |
| SCHEMBL1090149 | 0.85 | SIGMAR1 (0.54) | GAAHPGDDPP4CA1CA2 | |
| SCHEMBL29050293 | 0.85 | HPGD (0.48) | GAAHPGDDPP4CA1CA2 | |
| Hydrochloric Acid SCHEMBL3710664 | 0.84 | SIGMAR1 (0.53) | GAAHPGDDPP4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204629-A1 | METHOD FOR PRODUCING CFTR ACTIVATOR COMPOUND AND INTERMEDIATE USED THEREFOR | 일동제약(주) | 2023-10-26 | — | — | WO | claimed |
| CN-115260180-B | Triazole condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260180-A | Triazole fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |