Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391928 | 1.00 | HPGD (0.47) | HPGDLRRK2HCRTR1HCRTR2NPC1 | |
| SCHEMBL29050335 | 0.82 | HPGD (0.37) | HPGDGLAKCNH2 | |
| SCHEMBL29050321 | 0.82 | POLB (0.42) | KCNH2 | |
| SCHEMBL2038295 | 0.81 | NNMT (0.44) | KCNH2 | |
| SCHEMBL3155020 | 0.78 | SMN1; SMN2 (0.37) | KCNH2 | |
| SCHEMBL2766836 | 0.77 | KCNH2 (0.35) | HPGDNPC1HTTKCNH2 | |
| SCHEMBL30354542 | 0.73 | DYRK1A (0.43) | HPGDTP53KCNH2 | |
| SCHEMBL1075375 | 0.73 | DYRK1A (0.36) | HPGDNPC1HTTTP53KCNH2 | |
| SCHEMBL2770307 | 0.73 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL29692824 | 0.73 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528857-A | MALT-1 modulators | 艾克斯赛安西娅人工智能有限公司 | 2023-08-01 | — | — | CN | disclosed |