Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068365 | 0.88 | KCNH2 (0.37) | DYRK1AKCNH2PTPN11 | |
| SCHEMBL4072478 | 0.82 | KCNH2 (0.42) | KCNH2ALDH1A1MAP4K4 | |
| SCHEMBL5751891 | 0.81 | ENPP1 (0.42) | DYRK1AKCNH2PTPN11 | |
| SCHEMBL28867703 | 0.75 | PTPN11 (0.38) | KCNH2PTPN11MAP4K4 | |
| SCHEMBL14358116 | 0.74 | PDE10A (0.39) | KCNH2PTPN11MAP4K4 | |
| SCHEMBL4068344 | 0.74 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL31391928 | 0.73 | HPGD (0.47) | KCNH2HPGDTP53 | |
| SCHEMBL29050355 | 0.73 | HPGD (0.47) | KCNH2HPGDTP53 | |
| SCHEMBL1223104 | 0.73 | CHRNB2 (0.53) | CHRNB2CHRNA4 | |
| SCHEMBL2770307 | 0.73 | KCNH2 (0.36) | KCNH2CHRNA4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4163276-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |