SCHEMBL29050754

SCHEMBL29050754

O=P(Cc1ccccc1)(OI)OI

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.48
TSHR P16473 2/20 0.42
KLK8 O60259 1/20 0.40
PLAU P00749 1/20 0.40
KLK2 P20151 1/20 0.40
KLK4 Q9Y5K2 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
EPHX2 P34913 1/20 0.39
HTT P42858 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CASP1 P29466 1/20 0.37
HSD17B10 Q99714 1/20 0.37
FDPS P14324 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
CALM1 P0DP23 1/20 0.36
ANPEP P15144 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29050744 0.78 HPGD (0.50) HPGDTSHRFDPSANPEPLAP3
SCHEMBL21638768 0.77 HPGD (0.48) HPGDTSHRKLK8PLAUKLK2
SCHEMBL21638771 0.77 HPGD (0.48) HPGDTSHRKLK8PLAUKLK2
SCHEMBL563700 0.77 HPGD (0.48) HPGDTSHRKLK8PLAUKLK2
SCHEMBL18526934 0.77 HPGD (0.48) HPGDTSHRKLK8PLAUKLK2
SCHEMBL563232 0.76 KLK8 (0.63) HPGDTSHRKLK8PLAUKLK2
SCHEMBL5850148 0.76 TSHR (0.61) HPGDTSHRALDH1A1
SCHEMBL366215 0.74 NPY5R (0.50) HPGDTSHR
SCHEMBL22321982 0.72 KLK8 (0.51) HPGDTSHRKLK8PLAUKLK2
SCHEMBL914767 0.72 NPY5R (0.49) HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116325164-A Optical filter, optical device, and light-absorbing composition 日本板硝子株式会社 2023-06-23 CN disclosed