⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435445 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL916768 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL291820 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL6731455 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL291000 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL291923 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL8456972 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL9149670 | 1.00 | TSHR (0.53) | — | |
| SCHEMBL290726 | 1.00 | — | — | |
| SCHEMBL292580 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104707-B1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE MEDICINE INC (US) | 2020-07-15 | — | — | EP | disclosed |
| US-10294233-B2 | Treatment of H. pylori infections using MTAN inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2019-05-21 | — | — | US | disclosed |
| US-20190016730-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2019-01-17 | — | — | US | disclosed |
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-20170066754-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-9572813-B2 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| EP-3104707-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | Albert Einstein College of Medicine, Inc. (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015123101-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-08-20 | — | — | WO | disclosed |
| US-20150202208-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |
| US-4909833-A | A 4-chlorophenyl ring substituted in position 1 of a triazolin-5-one ring | NIHON NOHYAKU CO., LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| US-4399146-A | Treatment of atherosclerosis with khellin-related furochromones | THE UPJOHN COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| US-4313881-A | 5-Hydroxyfurochromones | THE UPJOHN COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4313882-A | 7-Methyl-6-methylthio-, methylsulfinyl-, and methylsulfonyl-methyl-furochromones | THE UPJOHN COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4313883-A | ANTHIATHEROSCLEROSIS | THE UPJOHN COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4304722-A | Benzo[1,2-b:5,4-b']difuran-3(2H)-ones | THE UPJOHN COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| US-4284569-A | Antiatherosclerotic furochromones | THE UPJOHN COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| US-4281013-A | Antiatherosclerotic use of khellin and khellinin | THE UPJOHN COMPANY (US) | 1981-07-28 | — | — | US | disclosed |