Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435445 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL916768 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL291820 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL6731455 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL291923 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL8456972 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL9149670 | 1.00 | TSHR (0.53) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL290508 | 1.00 | — | — | |
| SCHEMBL290726 | 1.00 | — | — | |
| SCHEMBL292580 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183603-A1 | CLEAVABLE SURFACTANTS | PROMEGA CORPORATION | 2023-06-15 | — | — | US | disclosed |
| US-11624041-B2 | Cleavable surfactants | PROMEGA CORPORATION (US) | 2023-04-11 | — | — | US | disclosed |
| US-20200263110-A1 | CLEAVABLE SURFACTANTS | PROMEGA CORPORATION | 2020-08-20 | — | — | US | disclosed |
| US-10626349-B2 | Cleavable surfactants | PROMEGA CORPORATION (US) | 2020-04-21 | — | — | US | disclosed |
| US-20180187127-A1 | CLEAVABLE SURFACTANTS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-07-05 | — | — | US | disclosed |
| US-9816054-B2 | Cleavable surfactants | PROMEGA CORPORATION (US) | 2017-11-14 | — | — | US | disclosed |
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-20170066754-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-9572813-B2 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-20040229909-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-20040127708-A1 | Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | disclosed |
| EP-1375486-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-20030138864-A1 | Method for identifying an enzyme to design anti-cancer compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-07-24 | — | — | US | disclosed |
| WO-2003043631-A2 | METHOD FOR IDENTIFICATION OF TUMOR TARGETING ENZYMES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-30 | — | — | WO | disclosed |
| EP-1167375-A1 | ERYTHROMYCIN DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0751133-B1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138864-A1 | Method for identifying an enzyme to design anti-cancer compounds | RNASE1, GUSB, DPEP1 | TSHR 4521/4885THRB 4105/4885HSD17B10 260/4885 |
| US-20200263110-A1 | CLEAVABLE SURFACTANTS | SI, PRSS3, TMPRSS15 | TSHR 2971/4885THRB 4021/4885HSD17B10 1911/4885 |
| US-20040229909-A1 | Antiviral agent | ZC3HAV1, ZC3HAV1L, DUT | TSHR 4237/4885THRB 3764/4885HSD17B10 1428/4885 |
| US-11624041-B2 | Cleavable surfactants | SI, PRSS3, TMPRSS15 | TSHR 2971/4885THRB 4021/4885HSD17B10 1911/4885 |
| US-20180187127-A1 | CLEAVABLE SURFACTANTS | SI, PRSS3, TMPRSS15 | TSHR 2971/4885THRB 4021/4885HSD17B10 1911/4885 |
| US-10626349-B2 | Cleavable surfactants | SI, PRSS3, TMPRSS15 | TSHR 2971/4885THRB 4021/4885HSD17B10 1911/4885 |
| US-20040127708-A1 | Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity | DUT, PNP, INMT | TSHR 4421/4885THRB 3003/4885HSD17B10 837/4885 |
| US-20230183603-A1 | CLEAVABLE SURFACTANTS | SI, PRSS3, TMPRSS15 | TSHR 2971/4885THRB 4021/4885HSD17B10 1911/4885 |
| US-20170066754-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | TSHR 3427/4885THRB 3798/4885HSD17B10 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.