⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916768 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL8456972 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL9149670 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL6731455 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL290726 | 0.97 | — | — | |
| SCHEMBL291000 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL290508 | 0.97 | — | — | |
| SCHEMBL291820 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL291923 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL5435445 | 0.97 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101909451-A | Fungicidal mixtures II | BASF SE | 2010-12-08 | — | — | CN | claimed |
| CN-1244575-C | Sulfonylalkylamido hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2006-03-08 | — | — | CN | claimed |
| CN-1530372-A | Inhibitor of hecterocyclic oxoaminoethylol aminosulfonic amine reverse transcripted virus protenase | G.D.ɪ����˾ | 2004-09-22 | — | — | CN | claimed |
| CN-1311793-A | Anti-small RNA virus compound and preparation method and application thereof | AGOURON PHARMA (US) | 2001-09-05 | — | — | CN | claimed |
| CN-1186499-A | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-07-01 | — | — | CN | claimed |
| CN-1183767-A | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-06-03 | — | — | CN | claimed |
| CN-1183102-A | Heterocyclic carbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-05-27 | — | — | CN | claimed |
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | claimed |
| WO-1990006753-A2 | CANCER TREATMENT | SANDOZ AG (CH) | 1990-06-28 | — | — | WO | claimed |
| EP-0373658-A2 | Use of quinoline derivatives in treating cancer | SANDOZ AG (CH) | 1990-06-20 | — | — | EP | claimed |
| EP-0077754-A2 | Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives | SANDOZ AG (CH) | 1983-04-27 | — | — | EP | claimed |
| US-12006311-B2 | Compounds for use in preventing or treating cancer | FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRONINSTITUT DE RECERCA (ES) | 2024-06-11 | — | — | US | disclosed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| WO-2024083861-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | SELABTEC SCIENCES, SLU (ES) | 2024-04-25 | — | — | WO | disclosed |
| EP-4356909-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | Selabtec Sciences, SLU (ES) | 2024-04-24 | — | — | EP | disclosed |
| US-4281013-A | Antiatherosclerotic use of khellin and khellinin | THE UPJOHN COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0029557-A2 | 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-03 | — | — | EP | disclosed |
| US-4241078-A | Fungicidal 3-(N-acyl-N-arylamino)-gamma-butyrolactones and gamma-butyrothiolactones | CHEVRON RESEARCH COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-3968244-A | Chemosterilant and larvicidal imidothiocarbonates | AMERICAN CYANAMID COMPANY (US) | 1976-07-06 | — | — | US | disclosed |