Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30082296 | 0.83 | MKNK1 (0.42) | KDRJAK2TYK2JAK1CCNA2 | |
| SCHEMBL27868737 | 0.81 | MKNK1 (0.41) | KDRJAK2TYK2JAK1CCNA2 | |
| SCHEMBL29603900 | 0.78 | KDM4E (0.48) | KDRJAK2TYK2JAK1CCNA2 | |
| SCHEMBL24181594 | 0.78 | KDM4E (0.48) | KDRJAK2TYK2JAK1CCNA2 | |
| SCHEMBL27564107 | 0.77 | JAK2 (0.46) | KDRJAK2TYK2JAK1MKNK1 | |
| SCHEMBL29050797 | 0.77 | ADRA2A (0.56) | KDRJAK2TYK2JAK1CCNA2 | |
| SCHEMBL30053750 | 0.77 | ADRA2A (0.56) | KDRJAK2TYK2JAK1CCNA2 | |
| SCHEMBL24181659 | 0.75 | PLAU (0.42) | KDRJAK2TYK2MEN1MAPK10 | |
| SCHEMBL30082269 | 0.75 | P2RX7 (0.50) | MEN1KMT2AGSK3A | |
| SCHEMBL29050804 | 0.75 | P2RX7 (0.50) | MEN1KMT2AGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340559-A | Preparation and application of SHP2 phosphatase heterocyclic inhibitor | 药雅科技(上海)有限公司 | 2022-11-15 | — | — | CN | disclosed |