SCHEMBL29051485

SCHEMBL29051485

CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NC(C)(C)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.49
▸ MDM4 O15151 2/20 0.45
▸ TP53 P04637 2/20 0.45
▸ CTSL P07711 1/20 0.44
▸ CTSB P07858 1/20 0.44
▸ CTSS P25774 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2D6 P10635 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ PIN1 Q13526 1/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355420 1.00 CASP3 (0.49) CASP3MDM4TP53CTSLCTSB
SCHEMBL29052325 0.90 CASP3 (0.45) CASP3MDM4TP53CTSLCTSB
SCHEMBL31453529 0.89 CASP3 (0.45) CASP3MDM4TP53CTSLCTSB
SCHEMBL29858341 0.86 CASP3 (0.45) CASP3MDM4TP53PIN1
SCHEMBL32669193 0.86 CASP3 (0.52) CASP3MDM4TP53KMT2A
SCHEMBL24580508 0.86 CASP3 (0.41) CASP3MDM4TP53CTSLCTSB
SCHEMBL29697630 0.86 CASP3 (0.41) CASP3MDM4TP53CTSLCTSB
SCHEMBL30812611 0.86 CASP3 (0.42) CASP3MDM4TP53CTSLCTSB
SCHEMBL30582698 0.85 CASP3 (0.54) CASP3MDM4TP53CTSLCTSB
SCHEMBL31251126 0.85 CASP3 (0.51) CASP3CTSLCTSBCTSSPIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025130972-A1 SYNTHETIC METHOD FOR TIRZEPATIDE 深圳翰宇药业股份有限公司 2025-06-26 — — WO claimed
CN-119978100-A Tizepa Process for producing peptide 四川吉晟生物医药有限公司 2025-05-13 — — CN claimed
WO-2025092769-A1 PREPARATION METHOD FOR DUAL GIP AND GLP-1 RECEPTOR AGONIST 博瑞生物医药(苏州)股份有限公司 2025-05-08 — — WO claimed
CN-119930756-A Preparation method of dual receptor agonist of GIP and GLP-1 博瑞生物医药(苏州)股份有限公司 2025-05-06 — — CN claimed
CN-119350471-B Tenipout peptide synthesis method 中肽生化有限公司 2025-04-25 — — CN claimed
CN-119529056-A Solid phase preparation method of telipopeptide 福建基诺厚普生物科技有限公司 2025-02-28 — — CN claimed
CN-119350471-A Tenipout peptide synthesis method 中肽生化有限公司 2025-01-24 — — CN claimed
CN-119331048-A Synthesis method of telipopeptide key intermediate 杭州信海医药科技有限公司 2025-01-21 — — CN claimed
CN-119219745-A Preparation of tel method of poisein 深圳翰宇药业股份有限公司 2024-12-31 — — CN claimed
CN-119101141-A Tenipout Process for producing peptide 苏州天马医药集团天吉生物制药有限公司 2024-12-10 — — CN claimed
CN-118005767-A Method for preparing Tirzepatide by combining solid and liquid 柏佳薇(深圳)生物科技有限公司 2024-05-10 — — CN claimed
CN-117304299-A Preparation method of Tirzepatide 深圳市健元医药科技有限公司 2023-12-29 — — CN claimed
CN-117106055-A Synthesis method of telipopeptide 杭州思诺达医药科技有限责任公司 2023-11-24 — — CN claimed
CN-116425827-A Short peptide Fmoc-L-Ile-Aib-OH and preparation method thereof 成都郑源生化科技有限公司 2023-07-14 — — CN claimed
CN-116120403-A Method for preparing Tirzepatide through solid phase 成都普康唯新生物科技有限公司 2023-05-16 — — CN claimed
CN-121914206-A Preparation method of short peptide Fmoc-Ile-Aib-Leu (S) -Asp (tBu) -OH and intermediate thereof 扬州奥锐特药业有限公司 2026-04-24 — — CN disclosed
CN-119529056-B Solid phase preparation method of telipopeptide 福建基诺厚普生物科技有限公司 2025-12-02 — — CN disclosed
CN-115806593-A Fatty acid chain modified double-receptor agonist and application thereof 成都普康生物科技有限公司 2023-03-17 — — CN disclosed
CN-115651075-A Synthesis method of Tirzepatide 杭州信海医药科技有限公司 2023-01-31 — — CN disclosed
CN-115160429-A Preparation method of Tirzepatide 深圳市健元医药科技有限公司 2022-10-11 — — CN disclosed
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