SCHEMBL32669193

SCHEMBL32669193

C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NC(C)(C)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.52
▸ MDM4 O15151 2/20 0.48
▸ TP53 P04637 2/20 0.48
▸ KMT2A Q03164 2/20 0.46
▸ EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31665894 0.88 PTPN1 (0.49) CASP3MDM4TP53
SCHEMBL27192645 0.87 CASP3 (0.46) CASP3MDM4TP53KMT2AEPHX2
SCHEMBL27206385 0.87 CASP3 (0.46) CASP3MDM4TP53KMT2AEPHX2
SCHEMBL29051485 0.86 CASP3 (0.49) CASP3MDM4TP53KMT2A
SCHEMBL31355420 0.86 CASP3 (0.49) CASP3MDM4TP53KMT2A
SCHEMBL119779 0.85 KMT2A (0.54) CASP3MDM4TP53KMT2AEPHX2
SCHEMBL29503775 0.85 KMT2A (0.54) CASP3MDM4TP53KMT2AEPHX2
SCHEMBL29362505 0.85 KMT2A (0.54) CASP3MDM4TP53KMT2AEPHX2
SCHEMBL30878000 0.83 CASP3 (0.53) CASP3MDM4TP53KMT2AEPHX2
SCHEMBL14407149 0.83 CASP3 (0.53) CASP3MDM4TP53KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035406-A1 SYNTHESIS OF GLP-1R/GIPR AGONISTS CARMOT THERAPEUTICS INC. (US) 2026-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035406-A1 SYNTHESIS OF GLP-1R/GIPR AGONISTS GLP1R, GIPR, GRPR CASP3 1940/4885MDM4 3842/4885TP53 4786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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