Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051803 | 1.00 | MEN1 (0.36) | MEN1KMT2AUSP30GPR119RBP4 | |
| SCHEMBL29051800 | 1.00 | MEN1 (0.36) | MEN1KMT2AUSP30GPR119RBP4 | |
| SCHEMBL14945259 | 0.92 | MEN1 (0.38) | MEN1KMT2AGPR119RBP4BACE1 | |
| SCHEMBL30065370 | 0.90 | MEN1 (0.38) | MEN1KMT2AUSP30GPR119RBP4 | |
| SCHEMBL30468471 | 0.85 | GRM5 (0.43) | MEN1KMT2AUSP30GPR119RBP4 | |
| SCHEMBL516800 | 0.84 | MEN1 (0.40) | MEN1KMT2AGPR119RBP4BACE1 | |
| SCHEMBL10187737 | 0.82 | SMN1; SMN2 (0.52) | MEN1KMT2AUSP30 | |
| SCHEMBL1441247 | 0.82 | SMN1; SMN2 (0.52) | MEN1KMT2AUSP30 | |
| SCHEMBL517028 | 0.81 | RBP4 (0.38) | MEN1KMT2AUSP30RBP4BACE1 | |
| SCHEMBL15032343 | 0.80 | GPR119 (0.55) | MEN1KMT2AUSP30GPR119GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |