Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903524 | 0.89 | EPHX2 (0.44) | KMT2ABTKPDE9ALMNAMAPT | |
| SCHEMBL30499571 | 0.87 | EGFR (0.40) | KMT2ADPP7BTKPDE9ALMNA | |
| SCHEMBL25272167 | 0.86 | BTK (0.46) | KMT2ABTKPDE9ALMNAMAPT | |
| SCHEMBL20645215 | 0.86 | PDE9A (0.48) | KMT2APDE9ALMNAMAPTCYP1A2 | |
| SCHEMBL21903644 | 0.85 | KMT2A (0.42) | KMT2ADPP7BTKPDE9ALMNA | |
| SCHEMBL21903640 | 0.85 | KMT2A (0.42) | KMT2ADPP7BTKPDE9ALMNA | |
| SCHEMBL21903828 | 0.85 | KMT2A (0.42) | KMT2ADPP7BTKPDE9ALMNA | |
| SCHEMBL25272291 | 0.84 | CYP1A2 (0.41) | KMT2APDE9ALMNAMAPTCYP1A2 | |
| SCHEMBL22010140 | 0.84 | PDE9A (0.42) | KMT2APDE9ALMNAMAPTCYP1A2 | |
| SCHEMBL30367510 | 0.84 | BTK (0.41) | KMT2ADPP7BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |