Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | HPGD | P15428 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25113694 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL29480773 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL27398352 | 0.79 | PDE5A (0.41) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL29052812 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTHTTMAPK1 | |
| SCHEMBL29052811 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTHTTMAPK1 | |
| SCHEMBL29480782 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTHTTMAPK1 | |
| SCHEMBL29079748 | 0.75 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL25113695 | 0.75 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL20266435 | 0.75 | HCAR3 (0.43) | KDM4EALDH1A1GAASMN1; SMN2PDE5A | |
| SCHEMBL20266434 | 0.75 | HCAR3 (0.43) | KDM4EALDH1A1GAASMN1; SMN2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547278-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116406360-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-07-07 | — | — | CN | disclosed |