Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL1249182 | 1.00 | THRB (0.63) | THRBTSHRMEN1KMT2AALDH1A1 | |
| Methoxymethane SCHEMBL3148055 | 1.00 | THRB (0.63) | THRBTSHRMEN1KMT2AALDH1A1 | |
| Methoxymethane SCHEMBL3792122 | 1.00 | THRB (0.63) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2809295 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9860990 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 | |
| Tetraethylene Glycol SCHEMBL8659912 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2367411 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2804854 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL863839 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL33376 | 0.96 | THRB (0.68) | THRBTSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1657239-B1 | Chromene compound | TOKUYAMA CORP (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-1655293-B1 | Chromene compound and articles comprising the same | TOKUYAMA CORP (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-1655294-B1 | Chromene compound and articles comprising the same | TOKUYAMA CORP (JP) | 2010-03-24 | — | — | EP | disclosed |
| EP-1184379-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-1657239-A2 | Chromene compound | Tokuyama Corporation (JP) | 2006-05-17 | — | — | EP | disclosed |
| EP-1655294-A2 | Chromene compound | Tokuyama Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| EP-1655293-A2 | Chromene compound | Tokuyama Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-6723859-B2 | BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES | TOKUYAMA CORPORATION (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20040014995-A1 | Chromene compounds | KAWABATA YUICHIRO (JP) | 2004-01-22 | — | — | US | disclosed |
| US-20030096117-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2003-05-22 | — | — | US | disclosed |
| EP-1184379-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2002-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014995-A1 | Chromene compounds | SMARCE1, SMARCB1, SMARCA2 | THRB 4750/4885TSHR 3923/4885MEN1 2481/4885 |
| US-20030096117-A1 | Chromene compound | SMARCE1, SMARCD2, SMARCB1 | THRB 4732/4885TSHR 3797/4885MEN1 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.