SCHEMBL2804854

SCHEMBL2804854

C=C(C)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.68
TSHR P16473 9/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 6/20 0.40
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 2/20 0.38
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.38
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863839 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL9860990 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
Di(Hydroxyethyl)Ether SCHEMBL18317889 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL629901 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL2809295 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
Tetraethylene Glycol SCHEMBL8659912 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL33376 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL2367411 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL864145 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1
SCHEMBL61385 1.00 THRB (0.68) THRBTSHRMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210244519-A1 PHOTOCURABLE COMPOSITION, DENTURE RELINE MATERIAL, AND KIT FOR PREPARING THESE TOKUYAMA DENTAL CORPORATION (JP) 2021-08-12 US disclosed
EP-3854820-A1 PHOTOCURABLE COMPOSITION, DENTAL PLATE LINER, AND KIT FOR PREPARING THESE Tokuyama Dental Corporation (JP) 2021-07-28 EP disclosed
US-10973740-B2 Powder-liquid type denture base lining material TOKUYAMA DENTAL CORPORATION (JP) 2021-04-13 US disclosed
EP-3488842-B1 POWDER-LIQUID TYPE DENTAL PLATE LINER TOKUYAMA DENTAL CORP (JP) 2021-03-24 EP disclosed
US-20190216689-A1 POWDER-LIQUID TYPE DENTURE BASE LINING MATERIAL TOKUYAMA DENTAL CORPORATION (JP) 2019-07-18 US disclosed
EP-3488842-A1 POWDER-LIQUID TYPE DENTAL PLATE LINER Tokuyama Dental Corporation (JP) 2019-05-29 EP disclosed
US-20100240840-A1 Resin Composition and multilayer optical member using the same HITACHI CHEMICAL CO., LTD. (JP) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10973740-B2 Powder-liquid type denture base lining material TAS2R8, TAS2R1, AOC1 THRB 4089/4885TSHR 2849/4885MEN1 4590/4885
US-20190216689-A1 POWDER-LIQUID TYPE DENTURE BASE LINING MATERIAL TAS2R8, TAS2R1, AOC1 THRB 4089/4885TSHR 2849/4885MEN1 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.