Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.89 |
| ▸ | DRD1 | P21728 | 1/20 | 0.89 |
| ▸ | BCHE | P06276 | 1/20 | 0.80 |
| ▸ | ACHE | P22303 | 1/20 | 0.80 |
| ▸ | DRD4 | P21917 | 1/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179207 | 1.00 | DRD2 (0.89) | DRD2DRD1BCHEACHEDRD4 | |
| SCHEMBL29373104 | 0.95 | DRD2 (0.89) | DRD2DRD1BCHEACHEDRD4 | |
| (R)-Reticuline SCHEMBL9587509 | 0.94 | DRD2 (1.00) | DRD2DRD1BCHEACHEDRD4 | |
| (R)-Reticuline SCHEMBL29364903 | 0.94 | DRD2 (1.00) | DRD2DRD1BCHEACHEDRD4 | |
| (R)-Reticuline SCHEMBL29373552 | 0.94 | DRD2 (1.00) | DRD2DRD1BCHEACHEDRD4 | |
| (S)-Reticuline SCHEMBL147597 | 0.94 | DRD2 (1.00) | DRD2DRD1BCHEACHEDRD4 | |
| (S)-Reticuline SCHEMBL147596 | 0.94 | DRD2 (1.00) | DRD2DRD1BCHEACHEDRD4 | |
| (S)-Reticuline SCHEMBL29923953 | 0.94 | DRD2 (1.00) | DRD2DRD1BCHEACHEDRD4 | |
| Laudanidine SCHEMBL18187574 | 0.92 | DRD2 (0.95) | DRD2DRD1BCHEACHEDRD4 | |
| Codamine SCHEMBL15696578 | 0.92 | DRD2 (0.91) | DRD2DRD1BCHEACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116656642-A | Rhizoma corydalis-derived oxymethyl transferase Cy4' OMT and application thereof | 中国中医科学院中药研究所 | 2023-08-29 | — | — | CN | disclosed |
| CN-116606829-A | Rhizoma corydalis-derived oxymethyl transferase CyS2OMT and functions thereof | 中国中医科学院中药研究所 | 2023-08-18 | — | — | CN | disclosed |