Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 known ✓ | Q96DB2 | 5/20 | 0.41 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitamide SCHEMBL29157933 | 1.00 | SOAT1 (0.46) | SOAT1MEN1KMT2AFAAHTP53 | |
| Oleamide SCHEMBL28302914 | 0.92 | FAAH (0.62) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitic Acid SCHEMBL7784973 | 0.89 | GPR84 (0.50) | MEN1KMT2AGPR84PPARGPPARD | |
| SCHEMBL28413906 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL29072296 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL1845513 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL28450507 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL2018663 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| Tetradecanamide SCHEMBL4193813 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL29164254 | 0.88 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102267025-A | No-clean low-rosin soldering flux | — | 2011-12-07 | — | — | CN | claimed |
| CN-113461970-B | Organic silicon wax emulsion and preparation method thereof | 浙江新安化工集团股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113461970-A | Organic silicon wax emulsion and preparation method thereof | 浙江新安化工集团股份有限公司 | 2021-10-01 | — | — | CN | disclosed |
| EP-2894185-B1 | ORGANIC POLYMER THIN FILM, AND METHOD FOR PRODUCING SAME | JAPAN SCIENCE & TECH AGENCY (JP) | 2017-11-29 | — | — | EP | disclosed |
| US-20170282130-A1 | ORGANIC POLYMER THIN MEMBRANE, AND METHOD FOR PRODUCING SAME | JAPAN SCIENCE & TECH AGENCY (JP) | 2017-10-05 | — | — | US | disclosed |
| US-9687793-B2 | Organic polymer thin membrane, and method for producing same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20150224452-A1 | ORGANIC POLYMER THIN MEMBRANE, AND METHOD FOR PRODUCING SAME | Japan Science and Technology Agency of Saitama | 2015-08-13 | — | — | US | disclosed |
| EP-2894185-A1 | ORGANIC POLYMER THIN FILM, AND METHOD FOR PRODUCING SAME | Japan Science and Technology Agency (JP) | 2015-07-15 | — | — | EP | disclosed |
| CN-104080438-A | Whitening cosmetic | AJINOMOTO KK | 2014-10-01 | — | — | CN | disclosed |
| CN-103843106-A | Electron-microscopic examination method for examining biosample while keeping said biosample unchanged, and composition for evaporation inhibition under vacuum, scanning electron microscope, and transmission electron microscope for use in said method | JAPAN SCIENCE & TECH AGENCY | 2014-06-04 | — | — | CN | disclosed |
| CN-100444821-C | Hair grooming preparation | KAO CORP (JP) | 2008-12-24 | — | — | CN | disclosed |
| US-20070233024-A1 | Sanitary Thin Paper and Process for Producing the Same | DAIO PAPER CORPORATION | 2007-10-04 | — | — | US | disclosed |
| CN-1977082-A | Sanitary thin paper and process for producing the same | DAIO SEISHI KK (JP) | 2007-06-06 | — | — | CN | disclosed |
| EP-1752580-A1 | SANITARY THIN PAPER AND PROCESS FOR PRODUCING THE SAME | Daio Paper Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
| CN-1829495-A | Hair grooming preparation | KAO CORP (JP) | 2006-09-06 | — | — | CN | disclosed |
| CN-1679480-A | Hair cosmetic composition | KAO CORP (JP) | 2005-10-12 | — | — | CN | disclosed |
| US-20050152929-A1 | High-quality; suitable as a raw material for cosmetics; good retention of liquidity and is unlikely to become cloudy on change of temperature | NEW JAPAN CHEMICAL CO., LTD., (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1498405-A1 | LIQUID VEGETABLE UNSATURATED ALCOHOL AND PROCESS FOR PRODUCING THE SAME | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2005-01-19 | — | — | EP | disclosed |
| CN-1178620-C | Personal care articles | — | 2004-12-08 | — | — | CN | disclosed |
| CN-1377240-A | Personal care articles | PROCTER & GAMBLE (US) | 2002-10-30 | — | — | CN | disclosed |