Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649128 | 0.83 | TSHR (0.60) | TSHRHSD17B10ALDH1A1HPGDPTPN11 | |
| SCHEMBL30494432 | 0.80 | PTPN11 (0.58) | THRATHRBTSHRHSD17B10PTPN11 | |
| SCHEMBL16136229 | 0.80 | PTPN11 (0.58) | THRATHRBTSHRHSD17B10PTPN11 | |
| SCHEMBL31412888 | 0.79 | ALDH1A1 (0.50) | TSHRHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL20430157 | 0.77 | HSD17B10 (0.45) | TSHRHSD17B10ALDH1A1HPGDPTPN11 | |
| SCHEMBL29053389 | 0.77 | PTPN11 (0.65) | THRATHRBTSHRPTPN11 | |
| SCHEMBL29053400 | 0.77 | MAPK1 (0.59) | THRATHRBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL9202658 | 0.75 | SIRT2 (0.54) | ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL29053394 | 0.75 | KDM4E (0.46) | THRATHRBTSHRHSD17B10HPGD | |
| SCHEMBL4649906 | 0.74 | ALDH1A1 (0.71) | TSHRHSD17B10ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396159-A | Synthesis method of 2,2' -biphenyl dicarboxylic acid compound | 湖南大学 | 2023-07-07 | — | — | CN | claimed |
| CN-116396159-A | Synthesis method of 2,2' -biphenyl dicarboxylic acid compound | 湖南大学 | 2023-07-07 | — | — | CN | disclosed |