Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197444 | 0.84 | XDH (0.53) | SIRT2HPGDXDHABL1MAPT | |
| SCHEMBL9198133 | 0.79 | SIRT2 (0.51) | SIRT2HPGDXDHMAPTHTT | |
| SCHEMBL4687529 | 0.78 | PARP15 (0.59) | SIRT2HPGDXDHHTTNPC1 | |
| SCHEMBL3341574 | 0.77 | HPGD (0.52) | HPGDMAPTHTTNPC1RAB9A | |
| SCHEMBL4282168 | 0.75 | FOS (0.50) | SIRT2XDHTP53KDM4EALDH1A1 | |
| SCHEMBL29053404 | 0.75 | THRA (0.49) | HPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8136810 | 0.74 | ALDH1A1 (0.47) | SIRT2XDHABL1MAPTHTT | |
| SCHEMBL17341985 | 0.74 | PARP10 (0.65) | HPGDMAPTNPC1PARP15KDM4E | |
| SCHEMBL27964225 | 0.73 | XDH (0.52) | SIRT2HPGDXDHHTTNPC1 | |
| SCHEMBL19962879 | 0.72 | MAOB (0.41) | HPGDXDHMAPTSMN1; SMN2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659047-A1 | HERBICIDAL BENZENE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994005153-A1 | HERBICIDAL BENZENE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-03-17 | — | — | WO | disclosed |