SCHEMBL29054191

SCHEMBL29054191

CCCC=Cc1cc(C(=O)O)oc1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
POLB P06746 3/20 0.38
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
PTPN11 Q06124 1/20 0.38
APEX1 P27695 3/20 0.37
PDE5A O76074 1/20 0.36
HSD17B10 Q99714 2/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 3/20 0.33
TLR8 Q9NR97 1/20 0.33
DAO P14920 1/20 0.33
MEN1 O00255 2/20 0.31
ALOX15 P16050 1/20 0.31
LIG1 P18858 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29807470 0.71 TDP1 (0.34) TDP1L3MBTL1POLBAPEX1HSD17B10
SCHEMBL22555846 0.71 DAO (0.39) TDP1L3MBTL1POLBAPEX1HSD17B10
SCHEMBL21815453 0.69 PTPN1 (0.61) TDP1POLBPTPN2PTPN1PTPN11
SCHEMBL19182828 0.69 TDP1 (0.54) TDP1L3MBTL1POLBAPEX1HSD17B10
SCHEMBL849075 0.68 MAPT (0.48) TDP1L3MBTL1POLBPTPN1PTPN11
SCHEMBL28407318 0.67 TDP1 (0.44) TDP1L3MBTL1POLBPTPN11APEX1
SCHEMBL4089995 0.66 PTPN1 (0.43) TDP1PTPN1KDM4EKMT2AALDH1A1
SCHEMBL28204968 0.66 PDE5A (0.33) PTPN2PTPN1PTPN11PDE5ATLR8
SCHEMBL8450311 0.66 CA1 (0.46) L3MBTL1POLBPTPN2PTPN1PTPN11
SCHEMBL2835105 0.65 RAB9A (0.44) TDP1POLBPDE5AKMT2ATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116601206-A Process for producing polyesters comprising 2, 5-furandicarboxylate units 福兰尼克斯科技公司 2023-08-15 CN disclosed