Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899678 | 0.86 | MEN1 (0.48) | MAPK1ALDH1A1TP53NPSR1LMNA | |
| SCHEMBL2897768 | 0.84 | — | — | |
| SCHEMBL1058304 | 0.83 | MAPK1 (0.58) | MAPK1 | |
| SCHEMBL2905021 | 0.82 | — | — | |
| SCHEMBL5927898 | 0.79 | POLB (0.50) | — | |
| SCHEMBL9688905 | 0.78 | GABRP (0.52) | MAPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL29049928 | 0.77 | LMNA (0.43) | MAPK1ALDH1A1KDM4ETP53NPSR1 | |
| SCHEMBL10961113 | 0.76 | MAPK1 (0.52) | MAPK1ALDH1A1TP53NPSR1PDE4B | |
| SCHEMBL10965056 | 0.75 | GABRP (0.57) | — | |
| SCHEMBL2903441 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982704-B1 | New molecular target of neurotoxicity | EXONHIT THERAPEUTICS SA (FR) | 2010-08-04 | — | — | EP | claimed |