Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 7/20 | 0.65 |
| ▸ | SRC | P12931 | 5/20 | 0.61 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909819 | 0.93 | MAPT (0.72) | MAPTGAATHRBCSF1RSRC | |
| SCHEMBL2913622 | 0.91 | CSF1R (0.66) | MAPTGAATHRBCSF1RSRC | |
| SCHEMBL2904593 | 0.88 | MAPT (0.64) | MAPTGAATHRBCSF1RMEN1 | |
| SCHEMBL2913855 | 0.87 | CSF1R (0.66) | MAPTGAATHRBCSF1R | |
| SCHEMBL2913881 | 0.87 | CSF1R (0.65) | MAPTGAATHRBCSF1RSRC | |
| SCHEMBL2911838 | 0.86 | MAPT (0.63) | MAPTGAATHRBCSF1RSRC | |
| SCHEMBL2911733 | 0.86 | CSF1R (0.66) | MAPTGAATHRBCSF1R | |
| SCHEMBL2912652 | 0.85 | MAPT (0.63) | MAPTGAATHRBCSF1R | |
| SCHEMBL2913852 | 0.85 | CSF1R (0.59) | MAPTGAATHRBCSF1RSRC | |
| SCHEMBL2910243 | 0.85 | CSF1R (0.59) | MAPTGAATHRBCSF1RSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |