Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280127 | 0.86 | EPHX1 (0.46) | EPHX1STSHPGDRECQLPTPN2 | |
| SCHEMBL20232906 | 0.84 | EPHX1 (0.45) | EPHX1STSHPGDRECQLPTPN2 | |
| SCHEMBL20213925 | 0.84 | EPHX1 (0.45) | EPHX1STSHPGDRECQLPTPN2 | |
| SCHEMBL29014961 | 0.81 | RECQL (0.49) | EPHX1STSHPGDRECQL | |
| SCHEMBL31320024 | 0.80 | RECQL (0.48) | EPHX1STSHPGDRECQL | |
| SCHEMBL57472 | 0.80 | HPGD (0.47) | EPHX1STSHPGDRECQL | |
| SCHEMBL29718457 | 0.80 | HPGD (0.47) | EPHX1STSHPGDRECQL | |
| SCHEMBL55991 | 0.80 | HPGD (0.47) | EPHX1STSHPGDRECQL | |
| SCHEMBL2146006 | 0.80 | HPGD (0.47) | EPHX1STSHPGDRECQLPTPN2 | |
| SCHEMBL2146010 | 0.80 | HPGD (0.47) | EPHX1STSHPGDRECQLPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362145-A | Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) inhibitors and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-11-18 | — | — | CN | disclosed |