SCHEMBL2905549

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2905546	1.00	CTSL (0.60)	CTSLCASP3USP30HDAC8HDAC3
	SCHEMBL2905746	0.89	CTSL (0.53)	CTSLCASP3HDAC8HDAC3HDAC4
	SCHEMBL2903098	0.89	CTSL (0.53)	CTSLCASP3HDAC8HDAC3HDAC4
	SCHEMBL2903093	0.89	CTSL (0.53)	CTSLCASP3HDAC8HDAC3HDAC4
	SCHEMBL2905965	0.88	CTSL (0.52)	CTSLCASP3USP30HDAC8HDAC3
	SCHEMBL2905961	0.88	CTSL (0.52)	CTSLCASP3USP30HDAC8HDAC3
	SCHEMBL2899984	0.87	HDAC8 (0.61)	CTSLUSP30HDAC8HDAC3HDAC4
	SCHEMBL2899982	0.87	HDAC8 (0.61)	CTSLUSP30HDAC8HDAC3HDAC4
	SCHEMBL2905625	0.81	HDAC8 (0.62)	CTSLUSP30HDAC8HDAC3HDAC4
	SCHEMBL2905629	0.81	HDAC8 (0.62)	CTSLUSP30HDAC8HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.