Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 2/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 3/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290062 | 0.84 | JAK2 (0.46) | ALDH1A1MAPTLMNA | |
| SCHEMBL290238 | 0.81 | SMN1; SMN2 (0.56) | BCL2L1CA12CA1CA2CA4 | |
| SCHEMBL4497703 | 0.75 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL289881 | 0.73 | SMN1; SMN2 (0.61) | BCL2L1CA12CA1CA2CA4 | |
| SCHEMBL20181224 | 0.73 | KDM4E (0.46) | ALDH1A1MAPTLMNA | |
| SCHEMBL2787018 | 0.72 | SMN1; SMN2 (0.41) | STK17BSTK17ACAMKK1AURKBCAMKK2 | |
| SCHEMBL299482 | 0.72 | APP (0.38) | STK17BSTK17ACAMKK1AURKBCAMKK2 | |
| SCHEMBL26500221 | 0.72 | APP (0.45) | BCL2L1STK17BSTK17AIKBKBHIPK4 | |
| SCHEMBL5148513 | 0.71 | APP (0.57) | BCL2L1IKBKBCYP19A1CA12CA1 | |
| SCHEMBL27651550 | 0.71 | APP (0.57) | BCL2L1IKBKBCYP19A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |