Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056286 | 0.90 | SLC22A12 (0.55) | PDE4BPDE4DSLC22A12MAPTGAA | |
| SCHEMBL29056213 | 0.89 | L3MBTL1 (0.48) | PDE4BMAPTCYP2C9KDRBRAF | |
| SCHEMBL29056261 | 0.88 | SLC22A12 (0.49) | PDE4BPDE4DSLC22A12MAPTGAA | |
| SCHEMBL29056193 | 0.86 | PDE4B (0.48) | PDE4BPDE4DMAPTKDRBRAF | |
| SCHEMBL29056239 | 0.83 | SLC22A12 (0.45) | PDE4BPDE4DSLC22A12MAPTGAA | |
| SCHEMBL29056228 | 0.81 | SLC22A12 (0.55) | PDE4BPDE4DSLC22A12MAPTPPARA | |
| SCHEMBL30542663 | 0.81 | PDE4B (0.56) | PDE4BPDE4DKDRBRAFPPARA | |
| SCHEMBL29056230 | 0.81 | PDE4B (0.41) | PDE4BPDE4DSLC22A12MAPTCYP2C9 | |
| SCHEMBL29056216 | 0.81 | PDE4B (0.56) | PDE4BPDE4DKDRBRAFPPARA | |
| SCHEMBL29056285 | 0.80 | PDE4B (0.39) | PDE4BPDE4DSLC22A12MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |