Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056285 | 0.83 | PDE4B (0.39) | PDE4BPDE4DPAX8JAK2JAK1 | |
| SCHEMBL29056279 | 0.80 | PDE4B (0.40) | PDE4BPDE4DPAX8JAK2JAK1 | |
| SCHEMBL30542663 | 0.80 | PDE4B (0.56) | PDE4BPDE4D | |
| SCHEMBL29056216 | 0.80 | PDE4B (0.56) | PDE4BPDE4D | |
| SCHEMBL29056209 | 0.79 | PDE4B (0.51) | PDE4BPDE4DKDM4E | |
| SCHEMBL30542622 | 0.79 | PDE4B (0.51) | PDE4BPDE4DKDM4E | |
| SCHEMBL29056200 | 0.78 | PDE4B (0.50) | PDE4BPDE4DKDM4E | |
| SCHEMBL30542648 | 0.78 | PDE4B (0.50) | PDE4BPDE4DKDM4ESYK | |
| SCHEMBL29056268 | 0.78 | PDE4B (0.54) | PDE4BPDE4DKDM4ESYK | |
| SCHEMBL30542629 | 0.78 | PDE4B (0.50) | PDE4BPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |