Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 15/20 | 0.60 |
| ▸ | GAA | P10253 | 15/20 | 0.60 |
| ▸ | SI | P14410 | 15/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 15/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22599893 | 0.84 | MGAM (0.50) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL8816910 | 0.81 | MGAM (0.60) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL29056520 | 0.81 | MGAM (0.68) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL29056738 | 0.81 | MGAM (0.68) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL5938 | 0.77 | DHODH (0.56) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL29967798 | 0.77 | DHODH (0.56) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL29411925 | 0.76 | PARP1 (0.72) | — | |
| SCHEMBL11199113 | 0.75 | MGAM (1.00) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL6511307 | 0.75 | MGAM (1.00) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL6511197 | 0.75 | MGAM (1.00) | MGAMGAASIMGAM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |