Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057665 | 0.84 | CHRM5 (0.43) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15183482 | 0.73 | KDM1A (0.38) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL27312162 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL21946781 | 0.72 | SMN1; SMN2 (0.55) | MEN1KMT2AALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL3126033 | 0.71 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL20076261 | 0.70 | KDM1A (0.36) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL29138679 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL25319811 | 0.69 | CYP4F2 (0.41) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6729367 | 0.68 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL10226086 | 0.67 | GNAI3 (0.39) | ALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438182-A | 7-azaindole compounds for inhibiting BCR-ABL tyrosine kinase | 活力疗法公司 | 2023-07-14 | — | — | CN | disclosed |