Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 3/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058025 | 0.89 | HTR6 (0.58) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL30395050 | 0.89 | HTR6 (0.58) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL29058026 | 0.87 | HTR6 (0.58) | HTR6HTR1AHTR3AADRB1 | |
| SCHEMBL29057926 | 0.85 | HTR6 (0.74) | HTR6HTR1AHTR7 | |
| SCHEMBL29057978 | 0.84 | HTR6 (0.58) | HTR6HTR1AHTR7 | |
| SCHEMBL29058052 | 0.84 | HTR6 (0.58) | HTR6HTR1AHTR3AADRB1MAPT | |
| SCHEMBL28311434 | 0.82 | HTR6 (0.57) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL30394603 | 0.82 | HTR6 (0.57) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL28312433 | 0.82 | HTR6 (0.57) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL29058019 | 0.81 | HTR6 (0.57) | HTR6HTR1AHTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |