Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17005041 | 0.93 | HSD17B10 (0.44) | HSD17B10HPGDRECQLGPR119PTPN2 | |
| SCHEMBL29059099 | 0.88 | HPGD (0.44) | HPGDRECQLGPR119PTPN2PTPN1 | |
| SCHEMBL26699680 | 0.87 | GPR119 (0.43) | HPGDRECQLGPR119EPHX2USP2 | |
| SCHEMBL20669397 | 0.85 | HPGD (0.48) | HPGDRECQLGPR119EPHX2USP2 | |
| SCHEMBL2340756 | 0.85 | HPGD (0.47) | HSD17B10HPGDRECQLGPR119EPHX2 | |
| SCHEMBL20669370 | 0.84 | HPGD (0.50) | HPGDRECQLGPR119EPHX2USP2 | |
| SCHEMBL15487760 | 0.84 | HPGD (0.56) | HSD17B10HPGDRECQLGPR119PTPN2 | |
| SCHEMBL484799 | 0.84 | HSD17B10 (0.49) | HSD17B10HPGDRECQLGPR119PTPN2 | |
| SCHEMBL24480361 | 0.82 | GPR119 (0.43) | HPGDGPR119EPHX2USP2SMN1; SMN2 | |
| SCHEMBL20669374 | 0.82 | GPR119 (0.43) | HPGDGPR119EPHX2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010858-B | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-112010858-A | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-12-01 | — | — | CN | disclosed |