Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533286 | 0.84 | ACHE (0.66) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL29059269 | 0.82 | TDP1 (0.51) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL11598343 | 0.82 | TDP1 (0.51) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL11646714 | 0.82 | TDP1 (0.51) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL29059334 | 0.82 | HTT (0.51) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL18697274 | 0.79 | TSHR (0.50) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL10931521 | 0.79 | TSHR (0.53) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL21551646 | 0.79 | TSHR (0.53) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL19101010 | 0.78 | TSHR (0.54) | TDP1GAATSHRCYP2C9HTT | |
| SCHEMBL27832701 | 0.78 | TDP1 (0.55) | TDP1SMN1; SMN2CYP1A2PPARGL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409664-B | Spiro heterocyclic tetrahydropyran compound and preparation method and application thereof | 河北威远生物化工有限公司 | 2023-07-18 | — | — | CN | disclosed |