Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18076004 | 0.86 | L3MBTL1 (0.57) | HTTLMNATDP1GAATUBB4A | |
| SCHEMBL7533286 | 0.84 | ACHE (0.66) | HTTLMNATDP1GAATSHR | |
| SCHEMBL24177014 | 0.83 | TUBB4A (0.60) | TDP1GAACYP2C9ACHETUBB4A | |
| SCHEMBL11598343 | 0.82 | TDP1 (0.51) | HTTLMNATDP1GAATSHR | |
| SCHEMBL29059062 | 0.82 | TDP1 (0.51) | HTTLMNATDP1GAATSHR | |
| SCHEMBL11646714 | 0.82 | TDP1 (0.51) | HTTLMNATDP1GAATSHR | |
| SCHEMBL29059269 | 0.82 | TDP1 (0.51) | HTTLMNATDP1GAATSHR | |
| SCHEMBL22580481 | 0.81 | TYR (0.58) | ACHE | |
| SCHEMBL22580428 | 0.81 | L3MBTL1 (0.56) | LMNATDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL12612639 | 0.81 | TUBB4A (0.40) | HTTLMNATDP1GAATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409664-B | Spiro heterocyclic tetrahydropyran compound and preparation method and application thereof | 河北威远生物化工有限公司 | 2023-07-18 | — | — | CN | disclosed |