SCHEMBL2905910

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2904936	0.85	AURKA (0.56)	AURKARPS6KB1AURKBCD38GBA1
	SCHEMBL2905911	0.82	EGFR (0.39)	AURKARPS6KB1AURKBCD38EGFR
	SCHEMBL3429529	0.82	AURKA (0.51)	AURKARPS6KB1AURKBCD38GBA1
	SCHEMBL4098815	0.73	AURKA (0.46)	AURKARPS6KB1AURKBCD38GBA1
	SCHEMBL2904940	0.69	GBA1 (0.47)	AURKARPS6KB1GBA1EGFRGLP1R
	SCHEMBL2906202	0.69	GBA1 (0.47)	AURKARPS6KB1GBA1EGFRGLP1R
	SCHEMBL666553	0.69	RPS6KB1 (1.00)	AURKARPS6KB1AURKBCD38EGFR
	SCHEMBL3428700	0.69	AURKA (0.40)	AURKARPS6KB1AURKBCD38CA1
	SCHEMBL3431331	0.69	AURKA (0.38)	AURKARPS6KB1AURKBCD38
	SCHEMBL2906297	0.69	AURKA (0.41)	AURKARPS6KB1AURKBGBA1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.