SCHEMBL2905913

SCHEMBL2905913

CC(C(=O)O)/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
TP53 P04637 1/20 0.35
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA4 P48169 2/20 0.31
GABRE P78334 2/20 0.31
GABRA6 Q16445 2/20 0.31
GABRG1 Q8N1C3 2/20 0.31
GABRG3 Q99928 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6454939 1.00 CYP1A2 (0.37) CYP1A2CYP3A4CYP2C9CYP2C19TP53
Propene SCHEMBL28435634 0.91 CYP1A2 (0.33) CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2416426 0.79 KDM4E (0.33) TP53GABRPGABRDGABRA1GABRB1
SCHEMBL346751 0.79 KDM4E (0.33) TP53GABRPGABRDGABRA1GABRB1
SCHEMBL346752 0.79 KDM4E (0.33) TP53GABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL9168486 0.77 KDM1A (0.32) TP53GABRPGABRDGABRA1GABRB1
SCHEMBL5981771 0.77 TP53 (0.43) TP53GABRPGABRDGABRA1GABRB1
SCHEMBL28808090 0.77 KDM1A (0.32) TP53GABRPGABRDGABRA1GABRB1
SCHEMBL29485701 0.76 TP53 (0.32) TP53
SCHEMBL1694420 0.75 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6900280-B2 Acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. (US) 2005-05-31 US claimed
US-4999216-A Method of coating concrete floors with photocurable coatings DESOTO, INC. (US) 1991-03-12 US claimed
US-4001160-A Aqueous emulsion adhesives based on C2 -C8 ethers of N-methylol amides copolymerized with vinyl esters in the presence of hydroxy functional protective colloids CHAS. S. TANNER CO. (US) 1977-01-04 US claimed
US-3941735-A Aqueous emulsion adhesive of a copolymer of an alcohol ether of N-methylol derivative of an allyl carbamate which develops water resistance through cure CHAS. S. TANNER CO. (US) 1976-03-02 US claimed
CN-104769182-B Polyacrylamide-type paper surface strength agent, and method for producing paper 星光PMC株式会社 2017-05-03 CN disclosed
EP-2000485-B1 Formaldehyde-free emulsion polymer dispersion composition including fully hydrolyzed polyvinyl alcohol as colloidal stabilizer provding improved heat resistance WACKER CHEMICAL CORP (US) 2010-08-11 EP disclosed
EP-2000485-A1 Formaldehyde-free emulsion polymer dispersion composition including fully hydrolyzed polyvinyl alcohol as colloidal stabilizer provding improved heat resistance Wacker Chemical Corporation (US) 2008-12-10 EP disclosed
WO-2008145489-A1 FORMALDEHYDE-FREE EMULSION POLYMER DISPERSION COMPOSITION INCLUDING FULLY HYDROLYZED POLYVINYL ALCOHOL AS COLLOIDAL STABILIZER PROVIDING IMPROVED HEAT RESISTANCE WACKER CHEMICAL CORPORATION (US) 2008-12-04 WO disclosed
US-6900280-B2 Acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. (US) 2005-05-31 US disclosed
US-6799636-B2 Methods and compositions for cementing in wellbores HALLIBURTON ENERGY SERVICES, INC. 2004-10-05 US disclosed
US-20040072978-A1 Compositions of acid macromonomers and their method of preparation CIBA SPECIALTY CHEMICALS CORP. 2004-04-15 US disclosed
EP-1392736-A2 ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION Ciba SC Holding AG (CH) 2004-03-03 EP disclosed
EP-0395243-B1 Inorganic particles ICI PLC (GB) 1994-01-19 EP disclosed
US-5084502-A Addition polymer blend with an acid group either mineral acid 1or carboxylic acid IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-01-28 US disclosed
US-5064718-A Precipitation in dipersant copolymer of acrylated polyether and acrylate monomer IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1991-11-12 US disclosed
US-4999216-A Method of coating concrete floors with photocurable coatings DESOTO, INC. (US) 1991-03-12 US disclosed
EP-0398487-A1 Aqueous dispersions of inorganic particles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-11-22 EP disclosed
EP-0395243-A2 Inorganic particles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-31 EP disclosed
WO-1990001512-A1 PHOTO-CURABLE VINYL ETHER COMPOSITIONS DESOTO, INC. (US) 1990-02-22 WO disclosed
EP-0307564-A2 Methods that introduce variations in color density into dyed cellulosic fabrics ECOLAB INC. (US) 1989-03-22 EP disclosed