SCHEMBL346751

SCHEMBL346751

CC(C)/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33
GABRG3 Q99928 2/20 0.33
GABRQ Q9UN88 2/20 0.33
ATM Q13315 1/20 0.33
TSHR P16473 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2416426 1.00 KDM4E (0.33) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL346752 1.00 KDM4E (0.33) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL28808090 0.97 KDM1A (0.32) KDM4EGABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL9168486 0.97 KDM1A (0.32) KDM4EGABRPGABRDGABRA1GABRB1
Methacrylic Acid SCHEMBL2015229 0.87 KDM1A (0.32) KDM4EATMKDM1A
2-Oxoisohexanoate SCHEMBL28858051 0.83 CA2 (0.35) KDM1AALDH1A1
SCHEMBL800041 0.82
SCHEMBL3161915 0.82
SCHEMBL5068658 0.82
SCHEMBL5981771 0.81 TP53 (0.43) KDM4EGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606850-B2 Synthesis of beta-hydroxyisovalerate and methods of use Sasya, Inc. (US) 2026-04-21 US claimed
EP-2196225-B2 Water-soluble agents in acrylate-based preparations BEIERSDORF AG (DE) 2025-04-30 EP claimed
US-12234495-B2 Synthesis of beta-hydroxyisovalerate and methods of use Sasya Inc. (US) 2025-02-25 US claimed
US-20250002949-A1 SYNTHESIS OF BETA-HYDROXYISOVALERATE AND METHODS OF USE Sasya Inc. 2025-01-02 US claimed
US-11920177-B2 Synthesis of beta-hydroxyisovalerate and methods of use Sasya Inc. (US) 2024-03-05 US claimed
EP-4320253-A1 SYNTHESIS OF BETA-HYDROXYISOVALERATE AND METHODS OF USE Sasya Inc. (US) 2024-02-14 EP claimed
CN-117500934-A Synthesis and use method of beta-hydroxyisovalerate 萨西亚公司 2024-02-02 CN claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20220325304-A1 SYNTHESIS OF BETA-HYDROXYISOVALERATE AND METHODS OF USE Sasya Inc. 2022-10-13 US claimed
WO-2022216868-A1 SYNTHESIS OF BETA-HYDROXYISOVALERATE AND METHODS OF USE Sasya Inc. (US) 2022-10-13 WO claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed
EP-0969793-A1 FOIL FOR WRAPPING HAIR ENDS Wella Aktiengesellschaft (DE) 2000-01-12 EP claimed
WO-1999029282-A1 FOIL FOR WRAPPING HAIR ENDS WELLA AKTIENGESELLSCHAFT (DE) 1999-06-17 WO claimed
EP-0589430-B1 Water-absorptive contact lens MENICON CO LTD (JP) 1999-06-16 EP claimed
EP-0605686-B1 EMULSION POLYMERS FOR USE IN HAIR FIXATIVES NAT STARCH CHEM INVEST (US) 1998-11-11 EP claimed
EP-0618262-B1 Polyacetal resin composition and sliding member OILES INDUSTRY CO LTD (JP) 1998-06-03 EP claimed
US-5634971-A AGITATING WITH A MIXTURE OF WATER AND A POLYOXYALKYLENE GLYCOL HAVING A BRANCHED ALCOHOL END GROUP; PRINTING INKS; ANTIAGGLOMERANTS PETROLITE CORPORATION (US) 1997-06-03 US claimed
EP-0114414-B1 PROCESS FOR THE PERMANENT WAVING OF NEWLY GROWN HAIR AND COMPOSITION FOR PERFORMING IT Wella Aktiengesellschaft (DE) 1988-06-01 EP claimed
US-4660580-A PREFERENTIAL; LIQUID AQUEOUS PRETREATMENT; IMMISCIBLE WITH PERMANENT WAVE SOLUTION WELLA AKTIENGESELLSCHAFT (DE) 1987-04-28 US claimed
EP-0114414-A1 Process for the permanent waving of newly grown hair and composition for performing it Wella Aktiengesellschaft (DE) 1984-08-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606850-B2 Synthesis of beta-hydroxyisovalerate and methods of use CYP51A1, CYP4Z1, CYP2U1 KDM4E 959/4885GABRP 616/4885GABRD 635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.