Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1238968 | 0.72 | KDM4E (0.44) | ALDH1A1LMNATP53HPGDSMN1; SMN2 | |
| SCHEMBL29059357 | 0.71 | GCK (0.32) | ALDH1A1KDM4EABL1 | |
| SCHEMBL4968048 | 0.68 | JAK3 (0.36) | ACACBDRD2DRD3MAPK10IRAK4 | |
| SCHEMBL27469633 | 0.67 | JAK3 (0.46) | ACACBMAPK10IRAK4JAK3MEN1 | |
| SCHEMBL20383930 | 0.67 | IRAK4 (0.43) | ACACBIRAK4 | |
| SCHEMBL19105571 | 0.67 | OPRM1 (0.40) | ACACBLMNASMN1; SMN2IRAK4 | |
| SCHEMBL12896071 | 0.66 | ALDH1A3 (0.35) | ACACBALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL24326416 | 0.65 | ALDH1A3 (0.34) | ACACBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18484467 | 0.65 | KMT2A (0.38) | ACACBALDH1A1LMNATP53POLB | |
| SCHEMBL21097265 | 0.65 | ALDH1A3 (0.34) | ACACBALDH1A1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601158-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-15 | — | — | CN | disclosed |